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May 2007;85(5):1428-1433

Intracellular GSH levels may be increased by upregulation of system Xc-expression, leading to cisplatin resistance in HNC cells (164)

Here, we report two cryo-EM structures of Ycf1 at 3.4 and 4.0 resolution in inward-facing open conformations that capture previously unobserved ordered states of the intrinsically disordered regulatory domain (R-domain)