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When the tightly knit structure and function are affected by various physiological and pathological stimuli, the integrity of the intestines barrier is compromised, allowing microorganisms and toxins to migrate throughout the body via the mucosa

Additionally, exploring the role of gut microbiota in health and CVDs will help to develop novel therapeutic interventions, including increasing vegetarian and dietary fiber content, restricting caloric intake, using probiotics/prebiotics or FMT regulation, and increasing exercise training, to prevent gut microbiota dysbiosis and reduce the occurrence of CVDs

Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

doi: 10.1038/s41418-019-0460-0 336 ZhouXWangGTianCDuLProchownikEVLiY