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The stronger fluorescence-bright spots revealed that the core-H 1 H 2 H 3 probes were successfully transported into the living cells and the core-HCR nano-assembling was achieved in the single cells

Recommended dosing of 1-2 mg subcutaneous injection 2-3x per week (6 mg/week total) compares to toxic dose estimated at ~22,500 mg (approximately 3,750 times higher than weekly dose)

Inducing ferroptosis or treating with IFN- in Institute of Cancer Research (ICR) mice exacerbates the symptoms of SS, while inhibition of ferroptosis or the IFN- signaling pathway in non-obese diabetic (NOD) mice models alleviates both ferroptosis in the salivary gland and SS symptoms

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Starting BPC-157 earlier in the injury process typically produces better results than waiting until problems become chronic