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In elderly individuals, the expression of p16 in skin melanocytes is higher due to damage to their telomeres ( In addition, senescent melanocytes can induce telomere dysfunction in fibroblasts and reduce keratinocyte proliferation ( Immune cells In the epidermis, LCs primarily activate nearby immune responses by presenting antigens to T cells

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The children were randomly assigned to receive either standard care therapy alone or standard care therapy for the respiratory infection plus a single oral dosage of 100,000 IU of vitamin D3, the children in the supplemented group did not experience a reduction in hospital stay duration, mortality, or ICU admission when compared to standard therapy alone [60]

doi:10.1177/070674371205700703 Bhatia P, Singh N

doi: 10.1136/pgmj.67.784.198