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Furthermore, therapeutic application of BV includes their use in the management of bursitis, tendonitis, dissolving scar tissue, in the management of post herpetic neuralgia, Lyme disease, rheumatoid arthritis, osteoarthritis, multiple sclerosis, TMDs, and more (Table 5) (Kurek-Grecka et al., 2020)

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Oral lesions depend on the toxin Oral lesions vary depending on the type of toxin involved

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This not only leads to a significant increase in ROS generation but also further amplifies the local inflammatory response by releasing pro-inflammatory signals (81)

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Chung KF (2011) Inhibition of p38 MAPK-dependent bronchial contraction after ozone by corticosteroids

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