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Functionality was preserved until 2020, when progressive paresthesia and paresis emerged in the left lower limb, later involving the left upper limb, with spasticity (predominantly left-sided) and dysarthria

Panelists found it difficult to use ANNEXA-Is findings to make regulatory recommendations that would affect a much broader set of patients who would have access to Andexxa

A case-control study of 164 patients with dementia of Alzheimer's type included 76 cases in which the diagnosis of Alzheimer's disease was confirmed by examination of brain cells after death

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Ongoing Treatment (Diet-Related): If your deficiency is linked to your diet, you may require a hydroxocobalamin injection twice a year