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Beyond statistical modeling, mass spectrometry-based multi-omics approaches, including genomics, proteomics, lipidomics, and metabolomics provide essential systems-level insights into how ENMs alter microbial physiology and cellular pathways, revealing widespread adaptations and stress responses at multiple biological layers ( Despite the robustness of these methodological frameworks, significant variability across studies underscores the need for standardized protocols

[134] and Pound et al

Methods: We retrospectively enrolled a total of 200 HCC patients with BDI from multicenter cohorts

Miller RG, Moore D, Young LA, Armon C, Barohn RJ, et al

Epigenetic regulation of the expression of genes involved in steroid hormone biosynthesis and action