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Activated Bak then causes the release of ROS, which form pores within the mitochondrial membrane

APXs are members of the class I peroxidases, which contain an heme group found in higher plants, green algae, red algae and protists (Kuo et al., 2020)

Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis

Patients with pure CARD9 deficiency often present with Familial chronic cutaneous and mucosal candidiasis (CMC), accompanied by stubborn infections in the skin, nails, and mouth, and some may have deep fungal diseases, making conventional treatment difficult to cure (Glocker et al., 2009)

doi: 10.1038/s41581-023-00694-0