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Sirt1 sustains female fertility by slowing age-related decline in oocyte quality required for post-fertilization embryo development

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Chronic Kidney Disease (CKD) Increasing evidence indicates that SUA is enhanced in patients with CKD (Liu et al., 2015)

The proper functioning of the SAC is crucial for the normal progression of meiosis in oocytes, and its dysfunction is a major contributor to aneuploidy in these cells

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