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Additionally, Tat-conditioned microglial EVs enriched for NLRP3 convey pro-inflammatory signals and contribute to synaptodendritic injury, further impairing neuronal structure and function [58]

Fucoxanthin is a unique antioxidant compound found in certain green superfoods

In patients with a fatal outcome, a skin biopsy is recommended for the establishment of cultured fibroblasts, along with anticoagulated blood for DNA isolation/immortalization of lymphocytes and stored frozen aliquots of plasma, serum and urine [81]