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Female volunteers applied GHK-Cu, encapsulated in a nano-lipid carrier twice a day over the course of 8 weeks using either carrier alone or the commercially available peptide Matrixyl 3000 as controls

Fathi-Kazerooni et al., 2022

Plant Cell 15, 16891703

Furthermore, BBR was shown to activate the Nrf2 pathway and inhibit the NF-kB pathway, hence reducing the buildup of ROS and mitochondrial dysregulation in ovarian tissues (Peng et al