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Comprehensive metagenomic analyses indicate that successful super donors must exhibit specific microbiological characteristics: a gut microbiota Shannon diversity index exceeding 3.5 (based on consensus gut microbiota diversity criteria where healthy adults demonstrate Shannon indices of 4.0-6.0, and certain studies report values above 3.5 as clinically normal in particular demographics) (133, 134)

Most patients are asymptomatic and not anemic throughout their life, but triggers can cause acute hemolytic anemia usually after a couple days

The result is that more of the active ingredient reaches deeper skin layers which compounds the benefit of better preservation

We identified 33 putative UgsL-interacting proteins (Supplementary Table 1)

The safety profile in the trial was consistent with what had been previously established for both treatments