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After all, it has already been established that delivering glutathione to the inside of the cell is vitally important because glutathione performs all its important roles as our master antioxidant inside the cell, not outside

Patel, and Steven E

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In Arabidopsis, SIR is encoded by a single, essential gene and is described as a bottleneck in the sulfate assimilation pathway ( SIR expression is rapidly upregulated in Arabidopsis and tomato in response to higher sulfite content, and accordingly SIR activity increases (Yarmolinsky et al., 2013)

This kind of targeted stack reflects the science: supporting mitochondrial function, glutathione production, and antioxidant defense simultaneously rather than relying on a single ingredient