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As expected, and consistent with a reduced interaction of the amidated C-terminal tyrosine with the CTR ECD, CagriP37Y presented a lower potency than Cagri in cells expressing CTR alone (Supplementary Fig

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All experiments followed the Guide for the Care and Use of Laboratory Animals published by the United States National Institute of Health (National Institute of Health Publication No

Once reconstituted, peptides face constant molecular collisions in the aqueous environment that can trigger aggregation, oxidation, and hydrolysis degradation that may not occur in the solid state

doi:10.1177/03635465241272393 Flores SE, Manatrakul R, Anigwe C, et al