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Synthetic analogues of PTH, such as Teriparatide (a recombinant form of PTH), have been approved by the FDA for human use and are used clinically to treat osteoporosis, a condition characterised by weak and brittle bones

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A 2015 study found that patients treated with 3mg methylfolate, 2 mg methylcobalamin and 35mg P5P experienced significant reduction in their symptoms as well as reduced pain 7

We refer to Supplementary Note 1 for more details on the cell-type dynamics and senescence in skeletal muscle

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