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In an in vivo study to evaluate anti-osteoarthritis activity in an osteoarthritis rat model induced by monosodium iodoacetate, the extract at 150 or 300 mg/kg reduced proinflammatory cytokine and mediator release, prevented cartilage degradation, and attenuated joint pain

References Campbell, J

Because methionine is converted to homocysteine and SAM, it is involved in many steps in fat metabolism