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Suzuki and Mittler, 2006)

In animal models, gene therapy has produced encouraging results, particularly concerning ABCB4, whether through vectors expressing ABCB4 or by focusing on the disease mechanism [98]

Beyond detoxification, the antioxidant machinery functions as a redox-sensitive signaling platform, mediating post-translational modifications and transcriptional reprogramming that fine-tune stress responses

Images were taken using a Zeiss LSM 780 Axio Imager 2 confocal laser scanning microscope with the operating software ZEN v.3.5

On the contrary, downregulating NNMT decreased the proportion of G2- and S-phase cells