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Most treatment plans come from clinical experience and available research

Hui-Hui Chen, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In the research framing, a cycle runs for a defined block of weeks followed by a break, with the rationale that the GH axis responds better to a stimulus that is not permanently present