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In lupus-prone mice, 4-OI ameliorates renal immune complex deposition, decreases autoantibody production, and attenuates hyperactivation of immune cells via inhibition of JAK1 [64]

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A study conducted by Jain and colleagues demonstrated that the elevated mtROS generated at complex III are required for TGF--induced gene expression (193)

Vanda Papp L, Holmgren A, Kum Khanna K, et al (2007) From selenium to selenoproteins: synthesis, identity, and their role in human health

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