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As neutrophils are depleted from the inflammatory site, blood monocytes, in contrast, accumulate and differentiate into inflammatory macrophages, which complete phagocytosis and destruction of the injurious agents [1-3]

Conversely, overcoming the blood-brain barrier, nanoparticle toxicity, and patient variability still remain as some of the obstacles that require further research

So, in that sense you get kind of lucky based on your proteins natural composition

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Adding to the significance of these findings, individuals with obesity were found to have higher circulating amounts of CREBH-C than non-obese individuals