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However, the help of PRP on injury healing is controversial, for example, a clinical follow-up found no difference between PRP and controls, these controversies may be related to the different ways of preparing PRP, more studies are needed to confirm the exact efficacy of PRP in tendinopathy

Our patient was diagnosed with severe GSSD after neonatal onset, with symptoms including hemolytic anemia, hyperbilirubinemia and severe metabolic acidosis (intractable), urine-organic acid analysis results suggestive of the presence of 5-oxoprolinuria, and imaging results suggestive of central nervous system damage and developmental retardation in the infant at follow-up

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Activation of the RAGE/STAT3 pathway in the dorsal root ganglion contributes to the persistent pain hypersensitivity induced by lumbar disc herniation

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