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More recently, the importance of the NRF2/HO-1 pathway in determining the outcome of M

Key findings: Our study demonstrates significant inverse associations between higher intakes of vitamin E, vitamin B6, and niacin and a reduced risk of developing cataracts, especially in high-intake groups

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The integrin 1/5/JNK/c-JUN signaling pathway in cancer cells is able to upregulate the higher matrix stiffness-induced lysyl oxidase like (LOXL)-2, then subsequently promote production of fibronectin, expression of MMP-9 and C-X-C motif chemokine ligand (CXCL)-12 and recruitment of BMDCs to encourage pre-metastatic niche establishment (95)