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Ribosome collision is sensed by the E3 ubiquitin ligase Hel2, which ubiquitinates uS10 and thereby induces the RQC pathway

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*Correspondence: Luhua Lai, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

10.1016/j.ejphar.2023.175746 60 HuangX

Biosafety of CeO 2 MnO 2 in vivo We systematically evaluated the potential toxicity of CeO 2 MnO 2 in synergistic treatment groups with X-ray, and the microscopic images of the tissues by H&E staining showed that CeO 2 MnO 2 combined with X-ray had no significant toxicity to the major organs of mice (Fig