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This was confirmed by using immunoblot analysis, with strongly decreased NBEAL2 levels 48h after transfection (Figure 6C)

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Science 367 , eaau6977 (2020)

Likewise, the Womens Health Initiative calcium plus vitamin D (CaD) trial reported no overall reduction in breast cancer incidence but observed a modest reduction in ductal carcinoma in situ (DCIS), suggesting potential long-term preventive effects under sustained supplementation (315)