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Therefore, pharmacological agents that mimic the effects of exercise become a potential treatment option

Free radicals and non-radical derivatives of oxygen are collectively termed reactive oxygen species (ROS) [1]

"SIRT1: roles in aging and cancer"

Target selection is essential

In primary cardiomyocytes (in post-myocardial infarction), the expression of SIRT1 and Phd3 were reduced, while cleaved caspase-3 and Hif-1 expression increased