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Impact of chemical endocrine disruptors and hormone modulators on the endocrine system

Curcumin exerts context-specific autophagy regulation through dual mechanisms: At moderate concentrations (2025 M), it promotes cytoprotective autophagy via inhibition of the mechanistic target of rapamycin (mTOR)-AKT axis (Zhao et al., 2016), evidenced by decreased p-AKT, p-mTOR, and p-P70S6K expression, coupled with increased microtubule-associated protein 1A/1B-light chain 3- II/microtubule-associated protein 1A/1B-light chain 3-I (LC3-II/LC3-I) conversion

Roos I, Sharmin S, Lechner-Scott J et al (2022) Comparison of the effectiveness of ocrelizumab vs interferon , fingolimod and natalizumab on relapses in RRMS

Skin naturally regenerates and melanin levels can fluctuate over time

In patients with PF, the progression of fibrosis is believed to be influenced by three primary factors: excessive epithelial damage caused by inhaled pollutants, senescence, and genetic susceptibility [32]