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Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

In AD, plaques of amyloid-beta and neurofibrillary tangles of tau are key pathological hallmarks

It encourages the production of telomerase, an enzyme that repairs and extends telomeres, supporting healthier cell replication

Cyclin D1 promotes the progression of the G1S phase, and tamoxifen can reduce the expression of cyclin D1, which is highly expressed in drug-resistant cells (Viedma-Rodriguez et al., 2014)