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10.1089/neu.2023.0438 J Neurotrauma

In a phase II trial, adults with a BMI of 30 or 27 kg/m with comorbidities were randomized to receive efpeglenatide at doses of 4 mg weekly, 6 mg weekly, 6 mg biweekly, or 8 mg biweekly, or a placebo, all combined with a hypocaloric diet [17]

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The cytokines IL-1, IL-6, TNF, and IFN are all implicated in contributing to liver damage

Results Mast cell infiltration was significantly elevated at the acute and sub-acute phase of stroke in human brains To investigate the importance of mast cells one of the primary responders after injury [10], we examined MCs in human brain samples from acute, sub-acute and chronic stroke patients