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Degradation of reduction-responsive disulfidated polymeric NPs triggered by GSH The The incorporation of a disulfide-bonded crosslinker within the micelle network provides a GSH-sensitive drug delivery that can be cleaved in the presence of high reducing agent concentrations prepared as follows: The samples (10 mg) were dispersed in PBS buffer with intracellular GSH concentration (pH = 6.4, 10 mM GSH) and then divided into four aliquots

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Mas o uso oral ou injetvel para fins estticos no Brasil no tem aval da Anvisa