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Tharmapalan, V

doi: 10.1046/j.1365-2958.2002.03072.x 26 Limon-PachecoJ.GonsebattM

The specific localization along with intense expression of these enzymes in renal carcinoma has led to the design of kidney-selective prodrugs that bypass earlier steps of the mercapturic acid pathway (GST, GT, and peptidase): these compounds include S -(guanin-6-yl)-L-cysteine ( S -(6-Purinyl)-L-cysteine (Hwang and Elfarra, 1991