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As a result, you start to feel more tired because the mitochondria are less efficient when they get oxidized or rusted. The free radical damage caused by oxidation then triggers your immune system to clean up the damage, which results in inflammation

When pushing your body to limits, you create more free radicals and burn through glutathione faster than your body can replenish

Biochemical Pharmacology, 85 (10), 1542-1554