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However, 2D cultures oversimplify the cellular architecture and fail to capture the complex brain microenvironment ( in vitro models (Zivko et al., 2024)

The safety and effectiveness of fondaparinux sodium have not been established in pediatric patients for the treatment of venous thromboembolism who are younger than 1 year old, weigh less than 10 kg, or with any category of renal or hepatic impairment

Combination use can increase complexity, cost, and risk

They also provide a lifeline to the many patients who are B12 deficient but remain untreated due to a within range result on a serum B12 test

Vitamin B12 supplements are usually safe