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The liver is the organ with the highest glutathione concentration in the human body

The limitation of monoculture is that it cannot explore the cell-ECM interaction and cannot well mimic the phenotype of liver fibrosis

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Findings from preclinical investigations using combined ovalbumin-induced and social disruption stress asthmatic mouse models have shown that anxiety or depression can promote increased activation of the HPA axis and glucocorticoid insensitivity, which augment airway inflammation and failure of glucocorticoid therapy in asthma

The authors monitored antioxidant defense mechanisms and found that replacing CBS function reduced myocardial oxidative stress