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In our previous report, a high-fructose diet (HFrD) activated hepatic de novo lipogenesis via ChREBP in mice [60]

Although milk thistle has demonstrated hepatoprotective effects in rats (2), further research is needed to establish similar success in humans

Both of which regulate mitochondrial biogenesis and shift substrate utilization from glucose toward fatty acid oxidation

As long as cellular glutathione is above a level considered to be adequate, which is called homeostasis, GCL is inhibited from making gamma-glutamylcysteine (GGC), no matter how much cysteine is available

Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease