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Reversible Conjugation of Isothiocyanates with Glutathione Catalyzed by Human Glutathione Transferases

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Assessment of the triangle test methodology for determining umami discrimination status

doi: 10.1016/j.celrep.2020.108571 64 GeissmannFManzMGJungSSiewekeMHMeradMLeyK

The bottleneck exploits random processes in the cell to increase the cell-to-cell variability in mutant load as an organism develops: a single egg cell with some proportion of mutant mtDNA thus produces an embryo in which different cells have different mutant loads