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Hydrogen sulfide (HS), a toxic gas with a characteristic odor, has gained attention for its dual role as both a pollutant and a signaling molecule in biological systems

doi:10.1016/j.freeradbiomed.2013.08.178 Kong AN, Owuor E, Yu R, Hebbar V, Chen C, Hu R, Mandlekar S (2001) Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)

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It is caused by nearly 200 different mutations that affect one or both of the beta globin chain genes on chromosome 11

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