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All experiments were carried out with at least three biological replicates

OSU-CG5 OSU-CG5 is an energy restriction mimetic agent that mimics glucose starvation and inhibits the mTOR pathway

The Loxl2-dm was then transferred to pAd-DEST vector (ThermoFisher) and used to generate adenovirus Ad-LOXL2-DM

5 Hallmarks of ferroptosis interact with PTSD pathogenesis 5.1 Iron metabolic disturbance Significant disturbances in iron metabolism have been confirmed in PTSD

Based on the established ability of CoQ10 in ROS generation, it was hypothesized that excess CoQ10 will enhance mitochondrial ROS production and activate cell death in cancer cells