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Multivariate Analysis

Phase I detoxification uses cytochrome P450 enzymes to break down toxins, but this process often creates highly reactive, intermediate metabolites that are actually more toxic than the original substance

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Table II [i] MASLD metabolic dysfunction-associated steatotic liver disease, ROS reactive oxygen species, MDA malondialdehyde, 4-HNE 4-hydroxynonenal, 8-OHdG 8-hydroxy-2-deoxyguanosine, ox-LDL oxidized low-density lipoprotein, NOX NADPH oxidase, CYP2E1 cytochrome P450 2E1, TGF- transforming growth factor , UCP2 uncoupling protein 2

Commipheroline Commiphora mukul resin extract, Resina Guggul: the spiny shrub native to the arid regions of India, Pakistan, and Bangladesh, produces a unique resin known as guggul resin