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This is because berberine derivatives can cross the blood-brain barrier and target mitochondria in the meantime (Wang L

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BPC-157 protects somatosensory neurons, promotes peripheral nerve regeneration after transection, counteracts the otherwise progressing course after traumatic brain injury, and in rat spinal cord compression models with tail paralysis, addresses axonal and neuronal necrosis, demyelination, and cyst formation while rescuing tail function

PMID: 215 LingGZhangMChenCWangYGaoQLiJet al