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Vitamin B12 shots may not be suitable for people with a history of: sensitivity to vitamin B12 Lebers disease, which affects the optic nerve kidney problems hypokalemia, or low potassium levels deficiencies in other nutrients, particularly folic acid and iron Vitamin B12 injections provide the individual with a synthetic version of vitamin B12

In older adults, reduced stomach acid levels can also limit the bodys ability to absorb B12 from food

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In the course of reducing reactions GSH is converted to its oxidized form (GSSG)