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Description

Iron metabolism in the body is associated with the development of T2DM

The order of calculations: molecular mechanics followed by semi-empirical followed by DFT minimized the chances of the structures being trapped in local minima rather than reaching global minima

doi: 10.1016/j.jconrel.2024.01.022 337 ChenHLiTLiuZTangSTongJTaoYet al

the method comprises reacting an epoxide of formula (XVI-1) bearing a protected hydroxyl group with an amino acid comprising conjugation partner of the formula (III) to provide a compound of the formula (XV-1a)