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Using the amount of dGSH adduct of acetaminophen formed under the same conditions as a reference, the adduct formation rates of anethole and pulegone correlated well with their toxicity profiles while those of eugenol and nordihydroguaiaretic acid did not

This may result in significant damage to cell structure, contributing to various diseases, such as cancer, stroke, diabetes, arthritis, hemorrhagic shock, coronary artery diseases, cataract, cancer, and acquired immune deficiency syndrome (AIDS) as well as age-related degenerative brain diseases [26]

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