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It is linked to histone modifications that regulate inflammatory pathways, with Nox5, a newly identified NADPH oxidase, serving a key role by generating superoxide, leading to oxidative stress and promoting As development

Made from amino acids in the liver, glutathione is an antioxidant that promotes tissue repair and weakens free radicals

Such organization could promote substrate channeling, enabling efficient substrate handoff between components of the complex without release into the bulk aqueous phase and thereby increase local substrate availability near ABCB7