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Wjtowicz, S., et al

Eur J Endocrinol (2022) 187:68596

GHK-Cu activates multiple cellular signaling pathways including MAPK/ERK, which upregulates collagen gene expression, and TGF-beta, which organizes the structural framework for new tissue formation

In vitro investigations often evaluate gene expression patterns, structural protein synthesis markers, and enzymatic activity related to extracellular matrix dynamics