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It functions as the bodys primary intracellular antioxidant, working inside cells to neutralize oxidative stress, assist the liver in binding and removing toxins, regulate immune cell activity, and support mitochondrial function

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97 Contemporary in vitro and in vivo evidence indicating a potential effect of N-acetylcysteine in IL-6 inhibition may stimulate further research to understand how the drug affects disease outcomes and maximize its benefits with concomitant pharmacotherapy to selectively inhibit the trans-signalling pathway through which IL-6 signals

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Studies observed that gut bacteria produce metabolites such as lipopolysaccharides (LPS), and short-chain fatty acids (SCFAs) that are directly associated with the -synuclein aggregation process ( Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, and Helicobacter pylori stimulate TLR4, triggering immune responses that lead to the production of pro-inflammatory cytokines, chemokines, and oxidative factors