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3a), with no significant relationship in several regions

Formulations should incorporate stabilizing technologies (such as ethosomes or encapsulation systems) to reduce irritation potential while enhancing permeation without overwhelming the skin barrier

It isnt yet clear if this leads to better outcomes than monotherapy, but it is a major question researchers are currently trying to answer

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Trace elements status in diabetes mellitus type 2: possible role of the interaction between molybdenum and copper in the progress of typical complications