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A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection

FEBS Lett 581:29472953 Eydallin G, Montero M, Almagro G, Sesma MT, Viale AM, Muoz FJ, Rahimpour M, Baroja-Fernndez E, Pozueta-Romero J (2010) Genome-wide screening of genes whose enhanced expression affects glycogen accumulation in Escherichia coli

Another study, currently in the recruiting phase, will focus on evaluating the safety and potential therapeutic efficacy of intravenous and sub-tenon delivery of cultured allogeneic adult umbilical cord-derived mesenchymal stem cells (UC-MSCs) for treating eye diseases, with the goal of assessing improvements in patient outcomes and identifying any adverse effects over a 48-month period (NCT05147701)

In MIR/I rats, Rb3 increased total antioxidant levels, induced PERK phosphorylation and nuclear translocation of transcription factor Nrf2, and promoted the expression of antioxidant genes such as HMOX1, thereby reducing the size of myocardial infarction (Sun et al., 2019)

In previous research, TST has been reported to inhibit FOXM1 and the malignant behaviour of a variety of tumours, including colorectal cancer, breast cancer, lung cancer, acute lymphoblastic leukaemia, ovarian cancer, and even pancreatic cancer [10,11,12,13,14,15]