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Other promising bioactive agents, including salviolone and vestitol, have been shown to influence calcium signaling and neuroactive ligandreceptor interactions, contributing to cognitive improvement and reduced A deposition in experimental models (Liang et al., 2025)

There are also no published guidelines for appropriate dosing regimens and duration of treatment

Flavonoids (e.g., quercetin) and phenolic acids (e.g., salvianolic acid B) play pivotal roles in early-stage ALD by directly scavenging reactive oxygen species (ROS) and activating the Nrf2 pathway, thereby blocking lipid peroxidation and mitochondrial dysfunction (Yue et al., 2021)

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