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The levels of gomisin D, schisandrol B, kadsuranin, and kadlinolactone F in the roots are higher than in the fruits, and these metabolites are closely related to SCFs antioxidant and anti-inflammatory activities (52, 53)

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Patients with PCOS presenting with hyperandrogenic manifestations such as hirsutism, acne and alopecia may benefit from anti-androgen therapies (e.g., spironolactone, flutamide, or finasteride) that inhibit androgen synthesis or receptor activity, thereby ameliorating cutaneous and pilosebaceous symptoms (Lizneva et al., 2016)