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(1946) demonstrated that intravenously injected thiosulfate is rapidly distributed in the extracellular fluid space and that its renal excretion occurs by glomerular filtration

They are commonly prescribed for individuals with a deficiency in vitamin B12, including those with pernicious anemia, gastrointestinal disorders that affect absorption, or vegetarians who do not consume adequate amounts of vitamin B12 from their diets

Electrolyte imbalance with excessive use or poor hydration

J Medicinal Chem

Coffee and tea may also lower blood sugar, but other drinks, especially alcohol and ones with sugar, should be kept to a minimum